Vita
Dr. Zeyuan Chen
Bioinformatikerin - PHENOME Projekt
Research interests
Molluscs are among nature’s greatest innovators, representing some of the most ancient and evolutionary successful animal radiations, with tremendous diversity in morphology, behavior, and lifestyle. What molecular mechanisms and driving forces produce such great adaptability and diversity? How are novel genes and functions generated, and how do different reproductive strategies and selection affect genetic diversity (genomic heterozygosity), adaptations, and population genomics? These questions fascinate me, and I look forward to finding answers from the Book of Life by ATGC.
- 03.2023 – present. Bioinformatician. Senckenberg Research Institute and Museum of Natural History Frankfurt am Main
- 10.2018 – 02.2023. Ph.D. Ludwig-Maximilians-Universität München; Zoologische Staatssammlung München. Studied Molluscan genomics under the supervision of Prof. Dr. Michael Schrödl. Funded by Marie Skłodowska-Curie Actions.
- 09.2015 – 07.2018. MS. Sichuan University. Studied genomics and population genetics under the supervision of Prof. Dr. Tao Ma.
- 09.2011 – 07.2015. BS. Quanzhou Normal University. Major Biotechnology.
Publikationen
14. Chen, Z, K Vončina, JD Sigwart (2025): Evaluating probe design for phylogenomics across taxonomic scales: First steps for applying ultraconserved elements in an understudied class (Mollusca: Polyplacophora) . — Molecular Ecology Resources. doi.org/10.1111/1755-0998.70076
13. Reyes-Tur, B, Chen Z, Gordillo-Pérez MJ, Ben Hamadou A, Gerheim C, Greve C, Sigwart JD (2025): Draft genome of the Cuban Painted Landsnail Polymita picta, International Mollusc of the year 2022. — BMC Genomic Data. 26:63.
12. Sigwart, JD, NLWS Wong, VL González, F Marcondes Machado, C Greve, T Schell, Z Chen (2025): Genome of the enigmatic watering-pot shell and morphological adaptations for anchoring in sediment. — BMC Genomics, 26, 460. doi:10.1186/s12864-025-11622-w
11. Chen, Z, A Baeza, C Chen, MT Gonzalez, V González, C Greve, K Kocot, P Martinez Arbizu, J Moles, T Schell, E Schwabe, J Sun, LWS Wong, M Yap-Chiongco, JD Sigwart (2025): A genome-based phylogeny for Mollusca is concordant with fossils and morphology. — Science. 387: 1001-1007. 10.1126/science.ads0215
10. Sigwart, JD, Y Li, Z Chen, K Vončina, J Sun (2025). Still waters run deep: Large scale genome rearrangements in the evolution of morphologically conservative Polyplacophora. — eLife 13:RP102542. doi: 10.7554/eLife.102542.3
9. Sigwart, J.D., Wong, N.L.W.S., González, V.L., Machado, F.M., Greve, C., Schell, T., Chen, Z. (preprint 2024): Genome of the enigmatic watering-pot shell reveals adaptations of a living suction anchor https://www.biorxiv.org/content/10.1101/2024.10.08.617303v1
8. Chen, Z., Doğan, Ö., Guiglielmoni, N., Guichard, A., Schrödl, M. (2022). Pulmonate slug evolution is reflected in the de novo genome of Arion vulgaris Moquin-Tandon, 1855. Sci Rep 12:14226.
7. Chen, Z., Schrödl, M. (2022). How many single-copy orthologous genes from whole genomes reveal deep gastropod relationships? PeerJ 10:e13285181.
6. Doğan, Ö., Schrödl, M. & Chen, Z. (2020). The complete mitogenome of Arion vulgaris Moquin-Tandon, 1855 (Gastropoda: Stylommatophora): Mitogenome architecture, evolution and phylogenetic considerations within Stylommatophora. PeerJ 8:e8603.
5. Chen, Z., Ai, F., Zhang, J., Ma, X. …& Ma, T. (2020). Survival despite isolation, inbreeding and asexual reproduction in the Tropics: insights from the genome of the world’s southernmost poplar (Populus ilicifolia). Plant J 103:430-442.
4. Su, Y., Bai, X., Yang, W., Wang, W., Chen, Z., Ma, J., Ma, T. (2018). Single-base-resolution methylomes of Populus euphratica reveal the association between DNA methylation and salt stress. Tree Genet Genomes 14:86.
3. Wang, W., Liu, H., He, Q., Yang, W., Chen, Z., Wang, M., Su, Y., Ma, T. (2017). Characterization of the complete chloroplast genome of Camptotheca acuminata. Conservation Genet Resour 9:241-243.
2. Chen, Z., Wang, W., Yang, W., Ma, T. (2016). Characterization of the complete chloroplast genome of Populus ilicifolia. Conservation Genet Resour 8:391-393.
1. Yang, W., Wang, W., Zhang, L., Chen, Z., Guo, X., Ma, T. (2016). Characterization of the complete chloroplast genome of Idesia polycarpa. Conservation Genet Resour 8:271-273.