The RA “Biodiversity Conservation” focuses on anthropogenic biodiversity changes (land use, pollution, invasion of neobiota, climate change), which amongst other things are associated with a loss of ecosystem services and thus are of central importance to human well-being. In this RA Senckenberg scientists analyze drivers and processes of such changes as well as their effects on the health of humans and the environment; we investigate how these biodiversity changes can be assessed in terms of nature conservation and derive sustainable mitigation, adaptation and management strategies. Central to this are innovative approaches such as methods of detection of species that are important to humans and those that are difficult to ascertain (for example through genetic monitoring, “environmental DNA”); the development of standard methods for the implementation of national and international environmental directives (for example, national mosquito monitoring) is also in our focus. Genetic wildlife monitoring is a flagship for international cooperation in data collection of endangered species. This RA also involves an intensive exchange with policy makers, authorities and other stakeholders; in this context contributions are made to relevant national and international reports and opinions (IPBES, IUCN). Strategic priorities are here e. g., the development of methods of “Next Generation Sequencing” and corresponding systems for biodiversity detection and the use of improved genetic detection methods (eDNA, Metabarcoding, Metagenomics) for aquatic and terrestrial systems.